Vitamin D, Reference Information

[west1]

This thread will be reserved for links to reference information for Vitamin D. For information on other vitamins/nutrients/herbs/supplements, please visit the other specifically named threads in this forum. For general information and links to references/databases/knowledgebases, please visit the Useful Websites and Reference Resources (http://neurotalk.psychcentral.com/showthread.php?t=1095) sticky thread for this forum. Also, not all research and reference information is currently in agreement for Vitamin D (dosage, etc.).

Forum members are encouraged to post additional Vitamin D reference links as desired.

Disclaimer: This information is intended for reference only. Any decision to initiate a vitamin or supplementation regimen should be discussed with a doctor or qualified medical professional.

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Vitamin D Specialty and Research Site:
http://www.vitamindcouncil.com/

Recent Research Paper on Benefits of Vitamin D (accessed via http://www.vitamindcouncil.com/ ):
http://www.vitamindcouncil.com/PDFs/CME-%20clinicalImportanceVitD.pdf (PDF format)

Vitamin D, General Information:
http://dietary-supplements.info.nih.gov/factsheets/vitamind.asp
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/vit_0265.shtml
http://lpi.oregonstate.edu/infocenter/vitamins/vitaminD/index.html
http://www.umm.edu/altmed/ConsSupplements/VitaminDcs.html (Univ. of Maryland & A.D.A.M., Inc.)
http://en.wikipedia.org/wiki/Vitamin_d
http://www.vitaminshoppe.com/content/en/healthguide/hncontent.jsp?org=VSI&ContentID=2930006&category=Supp&title=Vitamin%20D&type (Healthnotes, Inc.)
http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/otherendo/vitamind.html
http://www.supplementnews.org/vitamin-d/
http://www.healthy.net/scr/Article.asp?Id=2135
http://www.rd.com/content/openContent.do?contentId=1571
http://www.lef.org/magazine/mag2006/mar2006_report_vitamind_01.htm
http://www.lef.org/magazine/mag2003/apr2003_report_vitd_01.html

Vitamin D: Test, Deficiency, and Treatment Information:
http://www.mercola.com/2002/feb/23/vitamin_d_deficiency.htm
http://www.merck.com/mrkshared/mmanual/section1/chapter3/3d.jsp

Vitamin D, Overload and Toxicity Information:
http://en.wikipedia.org/wiki/Hypervitaminosis_D
http://www.nlm.nih.gov/medlineplus/ency/article/001594.htm
http://health.allrefer.com/health/hypervitaminosis-d-info.html
http://www.merck.com/mrkshared/mmanual/section1/chapter3/3e.jsp
http://www.prn2.usm.my/mainsite/bulletin/sun/1996/sun44.html

Vitamin D2 utilized in part to produce arteriosclerosis in rats in this study:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=10052017 (Abstract)
http://polaris.hoshi.ac.jp/frontier/hanin/seyama/pdf/5.PDF#search=%22Comparative%20effects%20of%20vitam in%20K2%20and%20vitamin%20E%20on%20experimental%20 arteriosclerosis%22 (Separate full text document, PDF format)

Vitamin D, News:
http://www.medicalnewstoday.com/medicalnews.php?newsid=40860
http://www.medicalnewstoday.com/medicalnews.php?newsid=27692
http://www.womentowomen.com/nutritionandweightloss/vitamind.asp
www.lef.org/magazine/mag2003/apr2003_report_vitd2.html

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Medline/PubMed (and other) Research Studies (Note: In PubMed, you may click the “Related Articles” link for similar studies). Full text reports are available for many of the following:

Vitamin D Dosage Studies:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12499343&itool=iconfft&query_hl=2&itool=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10232622&itool=iconfft&query_hl=6&itool=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17209171&itool=iconabstr&query_hl=1&itool=pubmed_docsum

Vitamin D Deficiency Studies:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15585791&itool=iconfft&query_hl=9&itool=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14661675&itool=iconabstr&query_hl=12&itool=pubmed_docsum

Other Vitamin D Studies:
http://www.lef.org/magazine/mag2006/abstracts/mar2006_abs_01.htm
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15585788&itool=iconfft&query_hl=6&itool=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10232683&itool=iconfft&query_hl=11&itool=pubmed_docsum

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Medication/Drug Interaction/Depletion Information (ref. Medication/Drug Induced Vitamin/Nutrient Interaction/Depletion References (http://neurotalk.psychcentral.com/showthread.php?p=32155#post32155) for general database/knowledgebase information):
http://www.vitaminshoppe.com/content/en/healthguide/hncontent.jsp?org=VSI&ContentID=3258003&category=Supp_Drugix&title=Vitamin%20D&type (Healthnotes, Inc.)
http://www.umm.edu/altmed/ConsSupplements/Interactions/VitaminDcs.html (Univ. of Maryland & A.D.A.M., Inc.)
http://www.umm.edu/altmed/ConsSupplements/Depletions/VitaminDcs.html (Univ. of Maryland & A.D.A.M., Inc.)

[mrsD]

Also Science News had a very good 2 part article recently on this subject:

http://www.sciencenews.org/articles/20041009/bob8.asp

and

http://www.sciencenews.org/articles/20041016/bob9.asp

[mrsD]

There is an interesting post in our Healthnews Headlines forum here:
Take a look:
http://news.yahoo.com/s/hsn/20060929/hl_hsn/vitamindcompoundmayfightbloodclotsincancerpatients

[mrsD]

Here is a new article this week.

Thanks to Silverlady for sending it on to me:

http://www.sciencenews.org/articles/20061111/bob9.asp
On the basis of more than 100 articles that he collected, Cannell and seven other researchers now propose that vitamin D deficiency may underlie a vulnerability to infections by the microbes that cathelicidin targets. These include bacteria, viruses, and fungi, the group notes in a report available online for the December Epidemiology and Infection.

This is only a hypothesis, "but a very credible one" that deserves testing, says immunologist Michael Zasloff of Georgetown University in Washington, D.C.

Behind the hypothesis are recent studies that link vitamin D intake to revved-up cathelicidin production. These investigations point to an infection-fighting role for vitamin D, which is produced in skin exposed to sunlight but is present in few foods.

[Lara]

Food for thought...

I live in a state of Australia where the rates of melanoma and skin cancer are extremely high. It used to be the highest rate in the entire world, not sure if it still is now. In the past year it has been suggested, based on studies from temperate climates in the world, that we are perhaps covering our skin too much when exposed to the sun. However, we don't live in a temperate climate so there is a lot of work being done in this area at the moment here in my state to clarify our individual situation. For decades we have been advised to cover our skin in the sun. We have a motto here that is just automatic now and one we've been teaching our children and our children's children, 'cause so many of the people my age have skin damage or worse from sun exposure. The aussie motto is Slip, slop, slap. Slip on a shirt, slop on the sunscreen, slap on a hat. Every Australian would know it. Now we're hearing conflicting reports... that we may have been covering up too much, or have we?

[EDITED to add: I forgot to add... my area has an average of about 300 days of sunshine a year. That's average. Some years much more, some less.]

Study of Vitamin D levels in Brisbane
<snipped article>
The results of our recent research suggest that some adult living in South East Queensland are also vitamin D deficient or have low levels of vitamin D (8% and 23% respectively). These unexpected findings suggest that some Queenslanders may have moderated their outdoor activity and clothing in order to protect themselves from UV.

Therefore, low vitamin D levels may be a public health issue for some population sub-groups living in sunny climates. However, as Queensland has extreme levels of ambient UV and a very high incidence of skin cancer, considerable attention needs to be paid to the accuracy of guidelines about maintaining adequate vitamin D levels through sun exposure and/or supplementation. Queenslanders need clear public health messages (formulated from evidence-based guidelines) that provide information about the relevance to them of media messages from more temperate climates. Health authorities will be unable to provide suitable guidance until a thorough investigation of the vitamin D levels of the Queensland population has been undertaken.

Pilot data generated by this project would also provide a basis for the further investigation of sensible evidence-based guidelines on UV exposure, which balance the need for sun-protection and adequate vitamin D levels, and consider the different requirements of people living in sub-tropical and tropical Australia. Such guidelines should reduce public confusion and prevent changes in behaviour which may ultimately lead to an increase in the incidence of skin cancer.
bold added by me.
http://www.uv.hlth.qut.edu.au/research/index.jsp
The Australian Sun and Health Research Laboratory
Institute of Health and Biomedical Innovation

from Cancer Council of Australia (http://www.cancer.org.au/documents/Risks_Benefits_Sun_Exposure_MAR05.pdf)
Risks and Benefits of Sun Exposure Statement

[NancyM]

I've been wondering how much D3 to take. I live in a sunny clime but I am photosensitive so I stay out of the sun. I'm currently taking 4,000 iu. I think that is about the right dose given that I really don't have any stores to draw on and that one article says a healthy man uses 3,000-5,000 iu per day.

Any suggestions? It sounds like up to 10,000 iu is probably safe.

[mrsD]

information.

I am still cautious about it. Part of that is my training, I suppose.:rolleyes:

If you suspect you are low in D, I would get a test at the doctor's.

Then you can monitor doses, if you choose to go into the thousand IU ranges.

I myself do not take more than 1000 IU per day (and none in the summer). Vit D is stored and over time,
high doses, can cause grief, including calcifications of the kidney.

[mrsD]

The see saw back and forth with Vit D is continuing:
This from our Health News forum:

http://news.yahoo.com/s/hsn/20070502/hl_hsn/highcalciumvitamindintakemayharmagingbrain

One of my colleagues is doing 10,000 units of D3 a day... I just won't go there, yet.

[west1]

The following link will direct you to multimedia presentations (webcast) by leading Vitamin D researchers from a Dec. 4-5, 2006 seminar entitled Contemporary Diagnosis and Treatment of Vitamin D-Related Disorders sponsored by the American Society for Bone and Mineral Research (http://www.asbmr.org/):

http://app2.capitalreach.com/esp1204/servlet/tc?cn=asbmr&c=10169&s=20343&e=6950&&

Other webcasts sponsored by this organization may be found here (http://www.asbmr.org/meeting/webcasts/index.cfm).

…

P.S.
Thanks to a poster at another neurology site for distributing information about this seminar.