View Full Version : Interesting Article
dbiker2
08-04-2008, 05:49 PM
The Neglected Side of Parkinson's Disease
http://www.redorbit.com/news/health/1507336/the_neglected_side_of_parkinsons_disease/
indigogo
08-04-2008, 05:58 PM
dbiker2 - thanks for posting this; annefrobert also posted this below.
What is Red Orbit? is this where this publication was first printed?
I think it is an accurate assessment of the current state of scientific knowledge of Parkinson's.
dbiker2
08-04-2008, 06:44 PM
Im not sure where red orbit is....i found the article on google
reverett123
08-04-2008, 07:08 PM
http://www.redorbit.com/
Check it out.
imark3000
08-06-2008, 12:54 PM
the article stresses what many members of this forum expressed often that pd characterization as merely a dopamine defficiency problem is dead wrong hence the need for a wholistic treatment and approach.please read
"Unmet Needs
Clearly, Parkinson's disease is more than just a dopaminergic illness. Further study of the nondopaminergic features may help physicians to identify and develop new therapies-and new strategies are sorely needed. Although levodopa is able to correct some of the most debilitating symptoms, eventually disability develops that this drug cannot control. What these people really need is a treatment that addresses the underlying cause of the affliction. Such a neuroprotective therapy would slow or, ideally, stop the disease in its tracks.
Of course, researchers would have much better results designing therapies to delay progression of the disease if they understood what caused it in the first place. Cell death in Parkinson's disease has been linked to several different factors, including accumulation of free radicals (molecules with unpaired electrons that are consequently highly reactive and can damage neighboring molecules), malfunctioning mitochondria (the energy powerhouses for cells), excitotoxicity (a pathological process by which excess levels of the neurotransmitter glutamate cause an influx of calcium ions that then kill or damage the cells), inflammation, apoptosis (programmed cell death) and the deficiency of certain cell-growth factors. In addition, recent research has indicated that the death of these neurons may be connected to an impairment in the cell's capacity to clear abnormal and misfolded proteins. This concept may provide an explanation for the presence of Lewy bodies, which may be the vehicle by which a nerve cell tries to remove, or at least segregate, these unwanted proteins. It is not immediately obvious, however, how all these different processes interact and whether they are necessarily the same from person to person. So although researchers may design neuroprotective strategies to target specific problem areas, a given approach may work for only a subset of patients-if it works at all.
"
Ibken
08-06-2008, 08:07 PM
the article stresses what many members of this forum expressed often that pd characterization as merely a dopamine defficiency problem is dead wrong hence the need for a wholistic treatment and approach.please read
"Unmet Needs
Clearly, Parkinson's disease is more than just a dopaminergic illness. Further study of the nondopaminergic features may help physicians to identify and develop new therapies-and new strategies are sorely needed. Although levodopa is able to correct some of the most debilitating symptoms, eventually disability develops that this drug cannot control. What these people really need is a treatment that addresses the underlying cause of the affliction. Such a neuroprotective therapy would slow or, ideally, stop the disease in its tracks.
Of course, researchers would have much better results designing therapies to delay progression of the disease if they understood what caused it in the first place. Cell death in Parkinson's disease has been linked to several different factors, including accumulation of free radicals (molecules with unpaired electrons that are consequently highly reactive and can damage neighboring molecules), malfunctioning mitochondria (the energy powerhouses for cells), excitotoxicity (a pathological process by which excess levels of the neurotransmitter glutamate cause an influx of calcium ions that then kill or damage the cells), inflammation, apoptosis (programmed cell death) and the deficiency of certain cell-growth factors. In addition, recent research has indicated that the death of these neurons may be connected to an impairment in the cell's capacity to clear abnormal and misfolded proteins. This concept may provide an explanation for the presence of Lewy bodies, which may be the vehicle by which a nerve cell tries to remove, or at least segregate, these unwanted proteins. It is not immediately obvious, however, how all these different processes interact and whether they are necessarily the same from person to person. So although researchers may design neuroprotective strategies to target specific problem areas, a given approach may work for only a subset of patients-if it works at all.
"
what if J Walton-Hadlock is largely correct with her theories as to the cause of PD? her therapy falls short of cure in all cases i know of, mine included, but her explanation of the cause of pd is the best i've found.. http://pdrecovery.org/pub_recovery.php it is iin fact the only likely explanation i've found.
what if the dead or dormant l-dopa cells are a result of - not a cause - of PD? maybe due to electric -- chi probs??
what if the cause is actually electrical disarray due to old subtle - or not - trauma/bloockage of meridians any where on the body - esp the foot/lleg/hip which is all the while impacting the healthy open channnels eventually as well? we are hay-wired!
what if PD, being body based.were treatable with body work? neuro's would be financially impacted for suure.. pd is biz. it is not in their best interest $ily to give pd up to others..:( especially one's who work below the neck!
this fact has a lot of weight, sadly.
aquario
08-07-2008, 12:03 AM
what if J Walton-Hadlock is largely correct with her theories as to the cause of PD? her therapy falls short of cure in all cases i know of, mine included, but her explanation of the cause of pd is the best i've found.. http://pdrecovery.org/pub_recovery.php it is iin fact the only likely explanation i've found.
what if the dead or dormant l-dopa cells are a result of - not a cause - of PD? maybe due to electric -- chi probs??
what if the cause is actually electrical disarray due to old subtle - or not - trauma/bloockage of meridians any where on the body - esp the foot/lleg/hip which is all the while impacting the healthy open channnels eventually as well? we are hay-wired!
what if PD, being body based.were treatable with body work? neuro's would be financially impacted for suure.. pd is biz. it is not in their best interest $ily to give pd up to others..:( especially one's who work below the neck!
this fact has a lot of weight, sadly.
Well, I'm giving it a try. dx'd 2 years ago, symptoms for 4-5. Not taking anything but CO-Q10, and supplements. And doing lots of different kinds of body work. Everything good so far; symptoms are manageable and much the same as a year ago. I've done some work with Janice Walton-Hadlock. She certainly is well-informed on the nature of parkinson's. I still don't know whether she's on to something, or just working from a left-field theory. I'll keep you all posted as to how the body work approach pans out.
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