Dimitris
05-17-2009, 01:12 PM
Hi,my name is Dimitris.Im Greek and my english isnt good
My father is a 62 yrs old, PD patient for 12 yrs taking medication seven in good condition,last 5 gradually getting worse...
Daily Drug cocktail using atm-->Stalevo 100mg x7,Madopar 250mg x7,Mirapexin 0,7 x4-7.
Doctors advise was to adjust doses and timers by himself.Hes definately overdosed,taking 2100mg L-Dopa(stalevo+Madopar) with carbidopa and entacapone in consideration probably near 3000mg L-Dopa.Same goes for the agonist(Mirapexin) since 4.5 tablets(0,7 mg) is the max daily dose.
12 yrs ago started treatment with L-Dopa(Madopar in small doses).6years later on Stalevo+madopar(even more L-dopa)and in the next 6 monts on Mirapexin(the agonist last...)mainly for stability issues.When my father started Mirapexin(0,18 in low doses)could finally walk without backwords steps,no dizzyness so it help him a lot.Time after time doses increased(doctors advise)for better effect until today(even when dyskinesia occured 4 yrs ago and got very worse the last 9 monts).Treated by 3 neuros in the last 12 yrs(other 2 consulted)every one of them was blaming the other doctor.
-Never had brain scan,nonone told him to do
-Never did L-Dopa Test
-Given antipsycotic drag to get some sleep ,non-combatible with L-Dopa treatment which made him a "vegetable"(Nozinan-maybe other drugs enchanted the effect or the prescribed dosage was bigger than it should) for 2-3 days and neuro told me dont bother at least hes is sleeping now...After this incident hes afraid drugs from this category(sleeping etc).
1) Dyskinensia problem.Only few hours per day in condition to walk properly without help.Many hours in Off condition.
2) Sleeping disorder.My mother,his 24/7 nurse told me he hasnt slept over 3 hour nighttime(with 1 hour straight sleep tops)the last 5-6 years.
3)Hallucinations,anxiety,aggressive behaviour,the last 2 years.Maybe he had hallucinations yrs before and kept it secret,dunt know.
---Every single on of those Madopar-Stalevo-Mirapexin could cause insomnia,Hallucinations,obssesion with some acts etc(overdosed),probably even worse in combination.He cant sit on a chair a long time without the urge to stand up,increased sexual desire,walking in a "strange-silly" way like "turbo-mode"so much energy,when hes in "on" condition, i could say this is from Mirapexins overdose but im not a doctor...Atm his "on-off" timers are messed-up,the off confition with dyskinesia is difficult for him and for family members that help.
Iwonder if there is a turning-back point after being poorly treated-observed(side-effects) and overdosed for a long period...Ihope there is.
My father is a 62 yrs old, PD patient for 12 yrs taking medication seven in good condition,last 5 gradually getting worse...
Daily Drug cocktail using atm-->Stalevo 100mg x7,Madopar 250mg x7,Mirapexin 0,7 x4-7.
Doctors advise was to adjust doses and timers by himself.Hes definately overdosed,taking 2100mg L-Dopa(stalevo+Madopar) with carbidopa and entacapone in consideration probably near 3000mg L-Dopa.Same goes for the agonist(Mirapexin) since 4.5 tablets(0,7 mg) is the max daily dose.
12 yrs ago started treatment with L-Dopa(Madopar in small doses).6years later on Stalevo+madopar(even more L-dopa)and in the next 6 monts on Mirapexin(the agonist last...)mainly for stability issues.When my father started Mirapexin(0,18 in low doses)could finally walk without backwords steps,no dizzyness so it help him a lot.Time after time doses increased(doctors advise)for better effect until today(even when dyskinesia occured 4 yrs ago and got very worse the last 9 monts).Treated by 3 neuros in the last 12 yrs(other 2 consulted)every one of them was blaming the other doctor.
-Never had brain scan,nonone told him to do
-Never did L-Dopa Test
-Given antipsycotic drag to get some sleep ,non-combatible with L-Dopa treatment which made him a "vegetable"(Nozinan-maybe other drugs enchanted the effect or the prescribed dosage was bigger than it should) for 2-3 days and neuro told me dont bother at least hes is sleeping now...After this incident hes afraid drugs from this category(sleeping etc).
1) Dyskinensia problem.Only few hours per day in condition to walk properly without help.Many hours in Off condition.
2) Sleeping disorder.My mother,his 24/7 nurse told me he hasnt slept over 3 hour nighttime(with 1 hour straight sleep tops)the last 5-6 years.
3)Hallucinations,anxiety,aggressive behaviour,the last 2 years.Maybe he had hallucinations yrs before and kept it secret,dunt know.
---Every single on of those Madopar-Stalevo-Mirapexin could cause insomnia,Hallucinations,obssesion with some acts etc(overdosed),probably even worse in combination.He cant sit on a chair a long time without the urge to stand up,increased sexual desire,walking in a "strange-silly" way like "turbo-mode"so much energy,when hes in "on" condition, i could say this is from Mirapexins overdose but im not a doctor...Atm his "on-off" timers are messed-up,the off confition with dyskinesia is difficult for him and for family members that help.
Iwonder if there is a turning-back point after being poorly treated-observed(side-effects) and overdosed for a long period...Ihope there is.