Quinolone type antibiotics cause PN, e.g. cipro,levaquin,avelox

[Nacho]

I doubt that people are lying on askapatient.com
I have found that the drug manufacturers and their reps lie more
to increase sales. They tend to massage the numbers to look good.
I find it curious that far more people (out of 500+) found Levaquin
harmful and damaging to them. Why would they make this up?

The quinolones have been around for over 30 years. Over half of
them have been pulled from the market due to toxic reactions.
They were originally designed for a last course of action when
nothing else worked. Due to big pharma greed, they are now com-
monly used first. A new Black Box warnig for permanent nerve damage
was released in 2004. Levaquin is one of the most dangerous ones.

[MelodyL]

Mrs. D:
You said: "Clindamycin is very hard on the GI tract, but is useful for deep tissue infections and bone infections(anaerobic). It can cause severe colitis in some people. It is called a lincosaminde."


Uh, I'm looking at a bottle of Clindamycin right in front of me. Dated 12/26/05. It was prescribed for me before my dentist's appointment in the beginning of January 2006 because I have mitral valve prolapse. I took 4 capsules prior to my appointment for a cleaning. I also had two crown two weeks later so I took some more then too.

Also, two years ago, for some dental work, I took this product. The dosage on the little bottle says 150 MG CA (don't know what CA means??)

Since we now know this didn't kill me, or have an negative affect on my GI tract, is it safe for me to take these when I have my next appointment (in two months). I have 8 pills left. Are they still good? I would hate to have to buy more, but I guess if I have to, I have to.

Now i was diagnosed with the beginning of neuropathy about May of 2006. Just the tips of my toes. I didn't get it from this drug did I?? I've been diabetic for 19 years.

Jeez, who knew that antibiotics could give you PN???

[kmeb]

When one has lots of drug allergies (I'm allergici to the cillans, sulfas) any of these are a problem - and PN - creates all kinds of problems! I was given CIPRO for assumed food poinsioning (was taken off it after 4 days due to bad side affects and the fact that the food poisioning tests came back negative) - but got C-Difficile Toxin from the Cipro... for the next six months I was in and out of the hospital being treated with Flagyl and Vancomycin (oral) to try to kill the C-Difficile - not only did the flaygl kill my C-Diff - but my sensory nerves (completely) I had mild nerve damage prior to starting treamtment - six months later (a week after finishing treatment - which had to be done repeatedly 'cause the C-Diff kept coming back) - I had no sensory nerve conduction and came to find out its a known neuro-toxin and can GIVE you PN - so if you already have it - you have to really stand up to your doc and find out alternatives.... I also havent had a meal of solid food since in almost 6 years because of the autonimic damage it caused.... my philosphy - never take anti-b's unles you KNOW you have an infection or Melody - with a heart condition (I have to do the same) - they usually give you a high dose of anti-b's the day you have work done - as a safeguard.....

[mrsD]

Clindamycin given in one dose, is not very problematic. It is common for dental
prophylaxis.

But a 10 day course for a tooth infection, may cause diarrhea.
When it first came out, it was targeted for acne. Acne treatments take several months. The colitis became apparent then as post marketing issues. When that happened Clindamycin was adapted for topical use only in acne. For a long time --several years--- Upjohn did nothing. So we had to compound the topical
products. These were time consuming and not my favorite by any means. Eventually Upjohn came out with Cleocin (brand) topical solution. Then the lotion came out, then the pledgettes/wipes. Now all 3 are available generically.
And I don't have to make it anymore!

I don't know of any PN issues with it.


I did not look at Levaquin today. I looked at Singulair, and one post said it increased the size of the user's p___s. You can see for yourself.
I have no doubt that some people do not have positive experiences with Levaquin or other fluroquinolones. That was documented long ago and written about by Stephen Fried. But in reading that website one must take into consideration that people post on the net sometimes unreliably and dishonestly. That website is not the only place one can find information.
I was not impressed with it, I could not find who owns it, and supports it,
and I found the drugs listed confusing, and at times inaccurate.

I only suggest one not take that site as gospel. It is unmoderated opinions only.

Raxar, Trovan and Omniflox were withdrawn. Omniflox within weeks of approval. It never really made it to shelves.
Tequin has been discontinued, due to diabetic toxicity. Raxar prolonged QT, and Omniflox caused kidney damage.

I agree that drug salespeople are told what to do and say to doctors by the companies they represent. This alone
has become a huge controversy, with ALL drugs, not just this family we are discussing here.

Thanks for the link...it was interesting today for me at least.

And here is a link to a --mycin that may be removed from the market --Ketek (telithromycin)
http://www.nytimes.com/2006/12/16/bu...tner=TOPIXNEWS

[MelodyL]

Thank you Mrs. D!!!!

As you can see, I am just nuts over these BestSmileys things!!!!

[Nacho]

A word of warning to anyone taking a quinolone type antibiotic-
Do not ever take an nsaid: advil, ibuprophen, alieve, ect. with the
quinolones. Most Drs don't know this. The warning is in fine print that
comes with your Rx of the quinolone. This is what contributes to the
adverse drug reactions being much much worse. Do not take steroids
with quinolones either.

After all my research and experience with cipro, I would recommend
that all quinolones be avoided unless it was a life or death situation.

That's just my laypersons opinion. Nacho

[Laurie43]

I took my last dose of avonex yesterday. I did know the risk as I had to take it in August. I was so sick and nothing would help but this antibiotic. I don't think any of us should take those drugs as a first try. But at this point I am fine. I have small fiber neuropathy in my legs. Only time will tell I guess.

Laurie