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Australian scientists discover key to halt nerve fibre damage in MS

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Unread 04-27-2012, 02:31 AM   #1
Koala77
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Default Australian scientists discover key to halt nerve fibre damage in MS

Scientists from RMIT and Monash Universities announced today a discovery that shows blocking a specific protein may have the ability to act as ‘hand brake’ to the progression of the disease in people with Multiple sclerosis (MS).

http://www.msra.org.au/australian-sc...ibre-damage-ms
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Unread 04-27-2012, 06:19 AM   #2
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They are certainly "mum" about the identity of this drug...which is already on the market.

I'm still searching for it. Finding other articles, but still no details.
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Unread 04-27-2012, 11:34 AM   #3
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Thanks Annie, yes what is it??
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Unread 04-27-2012, 11:54 AM   #4
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I finally gave up on looking this morning. I searched all the papers on PubMed by this guy.. Petratos S

The "approved" drug is not mentioned anywhere I could see.
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Unread 04-27-2012, 02:07 PM   #5
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My guess is that its a drug for HIV
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Unread 04-27-2012, 02:10 PM   #6
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It may be Lacosamide (LCM)....it blocks the crmp-2 protein (found in MS lesions) in epolepsy?

Read this http://www.ncbi.nlm.nih.gov/pubmed/22433297
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Last edited by SallyC; 04-27-2012 at 02:27 PM.
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Unread 04-27-2012, 04:22 PM   #7
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I couldn't find it either. I'll ask the neuro who is a MS specialist at new hospital I'm trying. Couldn't get appt. until 5/25. The hospital is a teaching hospital with a neuro clinic.
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Unread 04-27-2012, 04:49 PM   #8
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Lacosamide=Vimpat:

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000506/

In the study which Sally found, it was injected directly into the brains of the animals.

I wonder if this will ultimately end up helping TBI patients too?

Good work Sal!
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Unread 04-27-2012, 06:14 PM   #9
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Progesterone helped TBI...a lot. Back to MS. Hope you's track the compound down!
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Unread 04-30-2012, 11:46 AM   #10
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It sure would be nice to know. I suppose the drug companies must profit from this and thus make it secret until it's patented. Sounds like an important discovery!
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