Originally Posted by glenntaj
--and anecdotes are not data, etc., at the various neuropathy support groups I've gone to, and also at the large neuropathy convention in Washington I went to in late 2010, a number of people who did do laser/anodyne type therapies did report that their nerves did seem to "wake up" and cause them more discomfort for a while, and then gradually get better, though the effects varied widely.
We've had a number of people report on this board that nerves that were later proved to be regenerating often caused an increase in pain/parastheses for a time. I certainly noticed some weird flares that would start randomly and then fade in days/weeks. I've always suspected this occurs as the nerve growth cones proceed and have to fight through and around other structures, often undergoing some compression, and this involved irregular nerve signals that the brain must learn to re-interpret. This is why it can be difficult to know if one's new flare represents a progression of symptoms or a turn towards healing, except in long-term retrospect--a good reason to keep a symptom diary.
I completed a controlled test of five sessions of true laser therapy on my left palm, which suffers from Small Fiber Neuropathy. I then left the right palm (with the same problem) alone untreated as a control.
Sessions began at 2 minutes, then went to 5 minutes, and finished at 8 minutes in the final few sessions of my laser treatment sessions.
I then waited several weeks to see if I noticed any difference, and unfortunately to date have not noticed any improvement whatsoever.