Our beloved Houdini is still missing. It becomes more bleak every day... but we are still actively pursuing ways to find her.
If your homocysteine is good, which is it appears to be, that means you are converting it with B12, folate, and B6 properly.
If B12 or folate were not methylated properly, the homocysteine would build up in the blood.
If the values were higher, that would show either a B6 failure, or a methylation failure.
Cyanocobalamin and folic acid are not active forms of either B12 or folate. Both have to be changed (and this involves methylation-- adding methyl groups to each) This methyl group is then moved onto the homocysteine to create s-adenosyl methionine (SAM) which carries the methyl group around the body to perform many reactions we need for health (liver metabolism, joint maintenance, neurotransmitter synthesis).
Here is a map showing methylation:
The center circle is the methylation of folic acid to folate, which then moves on into the right hand circle of methylating homocysteine, and then SAM moves off that circle into the body.
This list shows all the places methylation takes place in our bodies:
Methylated versions of both vitamins exist now commercially which is relatively new, and helps people with genetic errors in conversion to them:
folic acid= methylfolate
Folate levels in testing are often mixed ..folate + folic acid.
These are often elevated when B12 is low. Also if you consume lots of fortified foods, or vitamins with folic acid in them, you will test higher in range.