I am really confused at the moment. I don't know why but I just felt the urge to read more about the latest news of lewy body dementia. I found the following article:
They tested rapamycin on a mouse model and they concluded it slows down the progression of neuron loss and improved motor function, even in the late stage of the disease. What confuses me about this is that in the PD community, if I am not wrong, this is not considered a valid treatment because it weakens your immune system. However, in this article they don't talk about it. So it is considered a valid treatment for LD but not for PD ??? This is very similar to the ganglioside story. For PD it is not considered a valid therapy because of a huge amount of supposed difficulties, but for HD it is valid treatment.
What even strikes me more is this article:
It says rapamycin is used for cancer and Alzheimer. So it is already in use for treatment of other diseases ? So why can't this be used for PD ? And indeed, it is used in other diseases as stated in the following article:
Anyway, I don't post to complain only, but also to pass information. As you can see from the first article rapacymin is supposed to work because of increased autophagy. So it's effect is supposed to be similar to gou teng. Besides this, there are many other autopaghy inducers they discovered:
spermidine, carbamazepine, and tamoxifen
What strikes me is this:
Tamoxifen treatment is linked with increased PD in women. I found similar reports for carbamazepine. This is really strange. On the other hand, I do remember that autophagy is good, but if there is too much autophagy it could attack your neurons, which could explain why people with no PD get PD after this treatment. So I guess you have to be carefull and be sure to stay in balance.