As a previous M.E. sufferer I am interested in this:
´There are two types of brain scan – a straight MRI scan which looks at the structure of the brain and functional SPECT scans which look at where there is activity in the brain. What was so fascinating about the many SPECT scans of M.E. patients’ brains that Dr Hyde showed us is that these scans appear to have great holes in them. That is to say, at any one moment there may be a large area of the brain that is completely non-functioning. Similar brain scans have been found in farmers with organophosphate poisoning and also with veterans of the Gulf War´
´So I’m suggesting that these large non-functioning areas of the brain may be caused by local mitochondrial failure, meaning there is simply no energy supply for those areas of the brain to function. They shut down and do the bare minimum, but no more. This begs the question as to why mitochondria shut down, and we now know there are lots of reasons for this. For instance, it can occur as a protective reflex against overwhelming viral stress, or in response to high insulin levels (secondary to high carbohydrate diets); it may be in response to damage from free radicals and cytokines, (the chemicals in the body which help fight infections), and certainly mitochondria can be directly poisoned by heavy metals, pesticides, carbon monoxide exposure and so on´
Taken from here:
One article read in M.E you forget where you put your keys but in Alzheimers you forget how
to use your keys. Well all the more reason for me to celebrate that those particular Alzheimer-like symptoms I had have been reversed!
I did find one
fmri imaging test for Myasthenia Gravis
and this reference originating from 1916 was ´intriguing´ - at least to me!!!:....´Associations between MG and psychosis
have been noted for over 90 years´
Taken from here:
With my own experiences of general fatigue and later specific myasthenic muscle fatigue cognitive dysfunction played almost a 100% role in M.E but only approximately 5% in M.G so have more connections with the former. I would still be very interested to see live brain scanning showing what parts of the brain are temporarily affected during various fatigable muscle weakness tasks in MG in comparison to a group of healthy subjects.
PS Alan - As someone with suspected MG I always find other people´s experiences interesting as well...