or due to inflammation/oxidative stress/fibrosis (or degeneration) and central sensitisation cycle
Even depression, psychosis and many mental disorders !
Like this :
It's always this thing. Always, always.
edit : lol, even psoriasis ! seriously.. an other exemple is cpps : http://en.wikipedia.org/wiki/Chronic...syndrome#Cause
Even TBI "Traumatic brain injury (TBI) evokes an intense neuroinflammatory reaction that is essentially mediated by activated microglia and that has been reported to act as a secondary injury mechanism that further promotes neuronal death."
Now to me it is a fact that nearly all diseases are driven by neurogenic inflammation itself.