lemon,
i tried DXM and got no symptom relief. i don't have tremor, maybe it will help your husband, maybe it won't. not sure why you feel compelled to post the papers supporting the possibility it might help, you don't have to convince me and its over the counter, it's a very low dose, just try it.
i have no idea why i don't have dyskinesias. i can't say that means i'm a slow progressor because when i'm "off" i just want to sit in a chair or lay down, i just happen to respond well to sinemet. when on, the avg. person wouldn't know i had pd. That's why i suggest you visit a pd support group and meet some advanced pd'ers rather than try to become an expert from browsing the internet.
i do know dyskinesias asre a result of having pd, not sinemet. dyskinesias are greatly reduced when the level of l-dopa is kept constant via a duodopa intestinal pump delivery and they actually increase the amount of l-dopa delivered with the pump. in fact, when oral l-dopa is administered after duodopa is stopped, it takes awhile for dyskinesias to start again, implying a physical change in neurons. dyskinesias can be created in advanced pd'ers from short lived agonists. so since most of us will need sinemet, your're delaying dyskinesias, not preventing them. and there are improved controlled release l-dopa formulations coming to market which will greatly reduce dyskinesias by themselves. so my layman's advice is not be so scared of sinemet. impax labs is hopefully going to get approval for such a drug shortly, hopefully insurance will pay for it.
i too was given a rx for requip when first diagnosed and told it was up to me if i wanted to use it. i didn't feel any pressure to fill the rx but was happy i had it so i wouldn't have to make another trip to the doctor. i waited 4-5 years before really taking meds full time, played around with mirapex which i couldn't tolerate so have seen on sinemet 5-6 years.
i suggest you get a used copy on ebay or amazon of "THE PARKINSON' DISEASE TREATMENT BOOK" by AHLSKOG, it's from a neuro that has a lot of pd experience.
l-dopa is a simple, natural occurring amino acid, it was a godsend when it was finally formulated with carbidopa to relieve pd, it is unfortunate that we have pd and we continue to progress but thank god we have sinemet. every central nervous system treatment, from autism to epilepsy to depression has side affects, the brain is a lot more complex than any other organ.
keep in mind that it's likely everyone active on this board has gone thru the same anxiety, literature searches, worries about drugs that you have posted. yet were're mostly all taking pharmaceutical drugs. even after years of trying everything mentioned on the internet, every supplement, every off label drug, were're taking sinemet and/or agonists, amantadine, azilect, COMT inhibitors, etc. so your're not the first person getting excited about DXM because they found some articles on the internet or read someone's anecdotes.
i apologize if i seem rude, but you seem to be lecturing me about sinemet and how your're sure DXM will relieve your husband's symptoms when he's tried neither. i don't get it.
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