CoQ10 & small nerve neuropathy

[Marie33]

Today I finally met a Doctor who was compassionate and caring! Update on me .. 2 years ago I was diagnoised with "Idiopathic" small fiber neuropathy by punch biopsy.My new Neurologist spent more then over an hour with me and was refreshingly honest. Because I am otherwise very healthy ,He will not accept my neuropathy as Idiopathic at this time. He wants to do more tests and said he will consult with a Neuromuscular Doctor at this Medical Ctr and will do some research this weekend. (wow) Ok Fast forward.. He recommends I take CoQ10 said to make sure I get the Ubiquinone form for Mitochondrial trtment. I have searched the internet and found this form CoQ10 very expensive. My question is does any one take CoQ10 for small nerve neuropathy, and what is the difference between Ubiquinone and Ubiquinol? The Doctor said to take 1000 mgs twice a day with a tsp of Olive Oil. I do not know anything about Coq10, but I read many PNers on here take it. This dosage seems like alot. Does anyone take Coq10 and how much do you take and does it help? I will wait for a response before I order it..Thank you in advance!

[mrsD]

That dose does sound very high.

Ubiquinone is the basic form. Ubiquinol is supposed to be the
activated form. Ubinquinol is still rather controversial and some
think it does not work well.

This link sells both, and has information you can read.

The new water soluble type, like Q-gel at this link enables lower dosing.
http://www.epic4health.com/whatiscoq10.html

Another brand out now that is more soluble is Qunol:
Walmart and Costco have this as well as Amazon.
4 months supply at 100mg a day is around $30.00
http://www.qunol.com/

Those really high doses of older CoQ-10 that does not have
the water solubilizing quality were used in treating some PD patients and some ataxia patients. That form needing olive oil, or some fat to go along with it, is not as current as the newer
solubilized types.

I think it is odd, that your doctor recommended such a high dose. I wonder if he knows about the newer forms?

[ginnie]

Hi, and I am sorry you have PN. I too have it and was the last person to believe these suppliments could help. I have taken coq10 for over a year now and there is marked improvement.
However your dose does seem high that the doctor recommended. I would call and ask if he said that, or meant 100mg.s 2 x day. When I did the research on this, that was a good dose. I would question taking that much. Mrs.D is very knowledgeable about these suppliments, and I would directly ask her as well.
The right combination of suppliments can work. A year ago, I was not walking very well. Now it is much better. Take care, and do the research as much as you can. ginnie

[mg neck prob]

Hi Marie.

Im not a exppert at all in supplements like Mrs D. I will tell you I found more than 300mg a day and I usually have to take it after eating a bigger meal like dinner.I started higher dose like your DR and it tore up my stoamch now 300 mg with meal I have no problems.

[Marie33]

Originally Posted by mrsD

That dose does sound very high.

Ubiquinone is the basic form. Ubiquinol is supposed to be the
activated form. Ubinquinol is still rather controversial and some
think it does not work well.

This link sells both, and has information you can read.

The new water soluble type, like Q-gel at this link enables lower dosing.
http://www.epic4health.com/whatiscoq10.html

Another brand out now that is more soluble is Qunol:
Walmart and Costco have this as well as Amazon.
4 months supply at 100mg a day is around $30.00
http://www.qunol.com/

Those really high doses of older CoQ-10 that does not have
the water solubilizing quality were used in treating some PD patients and some ataxia patients. That form needing olive oil, or some fat to go along with it, is not as current as the newer
solubilized types.

I think it is odd, that your doctor recommended such a high dose. I wonder if he knows about the newer forms?

MrsD
Thank you for your response. Its sounds like my Neuro was right in recommending I get the Ubiquinone form. Not so sure now about the dosage tho. Maybe you are right about him possibily not knowing about the newer forms. This is the first Doc Ive seen in 2 yrs that actually talked to me about supplementation! I will call him to let him know about my concerns. Do you think I should get the ubiquinone form or is the Coq10 others use just as effective? I hope to get some relief soon.

[Marie33]

Originally Posted by ginnie

Hi, and I am sorry you have PN. I too have it and was the last person to believe these suppliments could help. I have taken coq10 for over a year now and there is marked improvement.
However your dose does seem high that the doctor recommended. I would call and ask if he said that, or meant 100mg.s 2 x day. When I did the research on this, that was a good dose. I would question taking that much. Mrs.D is very knowledgeable about these suppliments, and I would directly ask her as well.
The right combination of suppliments can work. A year ago, I was not walking very well. Now it is much better. Take care, and do the research as much as you can. ginnie

Hi Ginnie,
Thank you for responding, Im sorry you have PN too. .. glad to hear you are responding well to suppliments. Do you take the ubiquinone form, or reg
CoQ10? How much do you take a day? Im trying to find the "right combination" but it gets all so confusing and overwhelming. Dont want to take anything that is going to cause more problems (side effects).For now Im taking all the B's..B12 Methyl, Benfoti B1, B6 , ran out of Folate, mag, fish oil, R-Lipoic Acid , ALCarnitine but not everyday RLA & ALC make me jittery. wish I could take them more often, I beleive they are the supplements that may help the most. Is Coq10 a stimulant? Im wondern how I will make this work..Thanks again.

[Marie33]

Originally Posted by mg neck prob

Hi Marie.

Im not a exppert at all in supplements like Mrs D. I will tell you I found more than 300mg a day and I usually have to take it after eating a bigger meal like dinner.I started higher dose like your DR and it tore up my stoamch now 300 mg with meal I have no problems.

Hi Mgneck
Glad you are having no problems with the ubiquinone! As MrsD stated, My Neuro is prbly not familiar with the newer forms. Im wondern if I could use the reg Coq10 and get the same results. If you dont mind me asking where you found 300mgs of the Ubiquinone and how much did it cost? Thank you so much..Marie

[mrsD]

We are talking major bucks here ...

example: 600mg:
http://www.puritan.com/co-q-10-055/c...-600-mg-030453

http://www.iherb.com/Healthy-Origins...-Softgels/4130

Perhaps 200mg of this would do compared to the old form:
http://www.epic4health.com/qgel-doub...0mg-coq10.html

I'd call him up and explain... Qunol 100mg a day should be enough IMO.

[mg neck prob]

Originally Posted by Marie33

Hi Mgneck
Glad you are having no problems with the ubiquinone! As MrsD stated, My Neuro is prbly not familiar with the newer forms. Im wondern if I could use the reg Coq10 and get the same results. If you dont mind me asking where you found 300mgs of the Ubiquinone and how much did it cost? Thank you so much..Marie

I ordered from puritan pride but the label shows it as Ubisuinol 300 mg -- it was buy one get one free $65 for a two month supply -- someone told me to buy in this from its better absorbed ---then ubiquinone but i maybe wrong .

[hopeful]

Originally Posted by Marie33

Today I finally met a Doctor who was compassionate and caring! Update on me .. 2 years ago I was diagnoised with "Idiopathic" small fiber neuropathy beg Cy punch biopsy.My new Neurologist spent more then over an hour with me and was refreshingly honest. Because I am otherwise very healthy ,He will not accept my neuropathy as Idiopathic at this time. He wants to do more tests and said he will consult with a Neuromuscular Doctor at this Medical Ctr and will do some research this weekend. (wow) Ok Fast forward.. He recommends I take CoQ10 said to make sure I get the Ubiquinone form for Mitochondrial trtment. I have searched the internet and found this form CoQ10 very expensive. My question is does any one take CoQ10 for small nerve neuropathy, and what is the difference between Ubiquinone and Ubiquinol? The Doctor said to take 1000 mgs twice a day with a tsp of Olive Oil. I do not know anything about Coq10, but I read many PNers on here take it. This dosage seems like alot. Does anyone take Coq10 and how much do you take and does it help? I will wait for a response before I order it..Thank you in advance!

Hi, I just started taking Qunol Mega CoQ10 100mg. Mrs. D's advice on what to take.

If I were you I would call your doctor and ask him why he suggested what he did and not what has been suggested here. I do tell my doctor I am on this site and what we suggest to one another. He is usually ok with things and agrees that certain supplements are worth trying. However, he has never suggested using any only says yes when I bring him information from this site.

I am really happy for you that you found a doctor you seem to like and he listens. I know how hard it is to find a good doctor. I am lucky I now have a rheumo and neuro that I love. They actually communicate with one another about my case. Good Luck with everything!