Immunosuppressants forever?

[AnnieB3]

And some have tried Tacrolimus/Prograf. It's a macrolide immunosuppressant though and is relatively contraindicated in MG and for those with a cancer history in their family.

Mestinon Syrup kicks in sooner than tablets. On average, Mestinon kicks in about 1/2 hour after taking it and wears off about 2-1/2 hours after taking it. Again, this varies per person somewhat. So, yeah, it's great having only two good hours of muscle strength.

Originally Posted by alice md

Where is the evidence for that?

I am not talking about abruptly stopping all medications in a dangerous way.

It took me nearly a year to cautiously decrease the dose of the steroids, even after I had no doubt that they only made my illness worse not better and I had a clear gradual improvement with every dose decrease. ( I went from being nearly bed-ridden and requiring respiratory support most of the day on 100 mg. every other day to being able to resume part time work when I was down to 10).

No evidence (you can only try and see what happens), but 2 docs told me this, and one of them is "the best" in the country I live.
But Im still reducing

[alice md]

Originally Posted by RavenC

No evidence (you can only try and see what happens), but 2 docs told me this, and one of them is "the best" in the country I live.
But Im still reducing

In my field of practice when a medication doesn't lead to significant improvement/ remission you don't keep on using it.
It doesn't make much sense in my humble opinion to have the side-effects without the benefit.

But, what do I know?

Originally Posted by alice md

In my field of practice when a medication doesn't lead to significant improvement/ remission you don't keep on using it.
It doesn't make much sense in my humble opinion to have the side-effects without the benefit.

But, what do I know?

True but this is just what they told me... And if 2 specialist tell you this, what else can you do? They just told me: once you started this, you're never going off it. Pitty they didn't tell me this when I started. However, my goal is reducing the dosage .

[alice md]

And if 2 specialist tell you this, what else can you do?

That is a tough question.

In such situations I resort to my dear friend Lewis C., who wrote a beautiful agony in 8 fits

http://ebooks.adelaide.edu.au/c/carroll/lewis/snark/

Which I hope he wouldn't mind me citing:

“Just the place for a Snark!” the Bellman cried,
 As he landed his crew with care;
Supporting each man on the top of the tide
 By a finger entwined in his hair.

“Just the place for a Snark! I have said it twice:
 That alone should encourage the crew.
Just the place for a Snark! I have said it thrice:
 What I tell you three times is true.”

[scrubbs]

[quote=
I don't know if I understand your question correctly (do you mean testing like in farmaceutical industry / scientific research?)
.[/QUOTE]

Yes

scrubbs