Will the MAPK pathway lead scientists to a cure for many common neurodegenerative diseases?
October 25, 2012 by pstreich
... In the paper “Pathological roles of MAPK signaling pathways in human diseases”, ...scientists are looking at a possible cell-signaling pathway that could shed light on a possible cure to these devastating diseases.
The basis of these three common neurodegenerative diseases involves either cell death or loss of neurons that leads to the symptoms that are developed from these diseases. Scientists have recently identified a few different cell-signaling pathways that could be involved in the development of these diseases. The first pathway that was identified is known as the Mitogen-activated protein kinase, or MAPK pathway. This pathway is associated with a number of different cellular activities that include cell proliferation, differentiation, survival, death and transformation. Other pathways in the body that were explored in this paper include the p38, JNK and ERK pathways, all of which are responsible for different cellular responses in the body...