Go Back   NeuroTalk Support Groups > Health Conditions M - Z > Parkinson's Disease

Parkinson's Disease Tulip

Pallido-thalamic tractotomy

Reply
Thread Tools Display Modes
Unread 02-03-2013, 10:47 PM   #1
lurkingforacure
Senior Member
 
Join Date: Feb 2008
Posts: 1,265
Default Pallido-thalamic tractotomy

First, thank you Olsen for that awesome link to Insightec's youtube video. If you go to their site and root around, you come up with this paper linked up, go to page 23, specifically for the discussion of PTT:

http://www.insightec.com/contentMana...0-%20Neuro.pdf

I followed up a bit and found this, check out those improvement scores, why have we not heard of this before?

"...At a follow-up of 14 6 months and in on-medication condition, a significant (P < 0.001) postoperative improvement of the motor part of the UPDRS (64.6%) and of the activities of daily living (ADL; 75.8%) was observed. Rest tremor, on-chorea and rigidity were reduced by 77.9, 92.2 and 82.3%, respectively. Distal and axial hypobradykinesias showed an improvement of 72.9 and 64%, respectively. Gait and postural stability also improved (57.5 and 66%, respectively) but at a lower level of significance (P < 0.005). Voice was not statistically influenced. L-dopa intake was decreased by 52.2% (P < 0.001) and 33% of the patients could be freed from treatment. In conclusion, PTT is an effective treatment for chronic therapy-resistant Parkinson's disease, improving symptoms in both on- and off-conditions."

from: http://journals.cambridge.org/action...ine&aid=398803

Average duration of these patients was 11+ years, also good news.

These articles are quite recent, October and December of 2012, and sound very promising. There are more articles out there about this if you google it, and with this technology, there is no drilling into the skull, can you imagine?

Granted, it's scary to think about slicing a nerve, which is what I understand tractotomy to be, but look at the trade-off, and compared to other options out there right now, or rather, lack of options, it is very appealing.

Does anyone know anything about this? They are currently using it, FDA approved, for uterine fibroids in the US and it has received EC in the EU.

GE Healthcare owns part of Insightec, fyi.
lurkingforacure is offline   Reply With Quote
"Thanks for this!" says:
Drevy (02-04-2013), Lemonlime (02-03-2013), olsen (02-05-2013)
Unread 02-04-2013, 07:59 AM   #2
Drevy
Junior Member
 
Drevy's Avatar
 
Join Date: Jan 2013
Location: Miami, Fl
Posts: 51
Default

Quote:
Originally Posted by lurkingforacure View Post
First, thank you Olsen for that awesome link to Insightec's youtube video. If you go to their site and root around, you come up with this paper linked up, go to page 23, specifically for the discussion of PTT:

http://www.insightec.com/contentMana...0-%20Neuro.pdf

I followed up a bit and found this, check out those improvement scores, why have we not heard of this before?

"...At a follow-up of 14 6 months and in on-medication condition, a significant (P < 0.001) postoperative improvement of the motor part of the UPDRS (64.6%) and of the activities of daily living (ADL; 75.8%) was observed. Rest tremor, on-chorea and rigidity were reduced by 77.9, 92.2 and 82.3%, respectively. Distal and axial hypobradykinesias showed an improvement of 72.9 and 64%, respectively. Gait and postural stability also improved (57.5 and 66%, respectively) but at a lower level of significance (P < 0.005). Voice was not statistically influenced. L-dopa intake was decreased by 52.2% (P < 0.001) and 33% of the patients could be freed from treatment. In conclusion, PTT is an effective treatment for chronic therapy-resistant Parkinson's disease, improving symptoms in both on- and off-conditions."

from: http://journals.cambridge.org/action...ine&aid=398803

Average duration of these patients was 11+ years, also good news.

These articles are quite recent, October and December of 2012, and sound very promising. There are more articles out there about this if you google it, and with this technology, there is no drilling into the skull, can you imagine?

Granted, it's scary to think about slicing a nerve, which is what I understand tractotomy to be, but look at the trade-off, and compared to other options out there right now, or rather, lack of options, it is very appealing.

Does anyone know anything about this? They are currently using it, FDA approved, for uterine fibroids in the US and it has received EC in the EU.

GE Healthcare owns part of Insightec, fyi.
This sounds excellent! I'd rather have non-surgical procedure done than to suffer one more day of these PD symptoms. I hope it becomes available soon.
__________________
John

Diag. Mar 2008 YOPD, @ age 39
Drevy is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
My SCS for Thalamic Pain Syndrome Poko SCS & Pain Pumps 6 01-30-2013 10:20 PM
Modulation Of VPM Thalamic Units By The Locus Ceruleus DocJohn Health News Headlines 0 09-29-2006 06:00 AM


All times are GMT -5. The time now is 03:52 PM.
Brought to you by the fine folks who publish mental health and psychology information at Psych Central Mental Health Forums

The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider. Always consult your doctor before trying anything you read here.


Powered by vBulletin • Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.


All posts copyright their original authors Community Guidelines Terms of Use Privacy Policy
NeuroTalk Archives