CoQ10... can you tell me about this if you have taken it?

[InHisHands]

Has this helped you? And in what way? I was considering taking it for my reflex sympathetic dystrophy, but is isn't cheap and I was wondering about anyone else's experinces with it. Really looking for someone who has nerve pain/ has taken it and their experience.

Thank you very much!!

[Jo*mar]

some general info on CoQ10
-
http://www.mayoclinic.com/health/coe...ient=firefox-a

http://www.herbalremedies.com/rsd.html

http://search.store.yahoo.com/cgi-bi...Fx%3FEvxbjwv4n

http://healthlibrary.epnet.com/GetCo...chunkiid=21682

[mrsD]

major studies of CoQ-10 for RSD.

However, for nerve neuropathy, there are studies for L-carnitine and acetyl carnitine.

CoQ-10 is used in high dose for Parkinson's, and some forms of ataxia.

CoQ-10 and carnitine are being used together today in products to prevent
damage and aging to mitochondria in cells. This is a antioxidant approach.

Since CoQ-10 is benign and has little if any negative effects, it certainly can not harm to try. But you would need high doses to get anywhere. I'd use it
with carnitine. Some products are already combined this way.

Both however are expensive, so it is a financial commitment. The PD board has people using high dose CoQ-10... you can ask there where they buy theirs.
I have seen products that claim for best results CoQ-10 and carnitine need some biotin as a helper. The product Juvenon has it added, for example. Biotin is a B vitamin.

There are hints that RSD is a calcium error in the nervous system, and
for a while now bisphosphonates are being tried for it:
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15367305
and this is what pamidronate is:
http://www.drugs.com/MTM/pamidronate.html

The theory is that calcium is over active in the NMDA channels, which are pain
generators. Magnesium counters calcium at the NMDA channel to some extent, and making sure you have enough magnesium may be helpful , but not curative, since RSD is still not fully understood.
http://www.helpforpain.com/arch2001feb.htm

We have a magnesium thread here:
http://neurotalk.psychcentral.com/showthread.php?t=1138

If you choose CoQ-10... choose one that is a soft gel cap with a label
that says it is enhanced absorption.
Powder forms are useless basically. The new Q-sorb and other names are
better. Here is one with a good formulation:
http://www.epic4health.com/noname.html
This supplier also has Carnitine
http://www.epic4health.com/lcar60cap.html
This is the same manufacturer as the Rx Carnitor.
I have used this supplier in the past. They are very good.

[ozone]

I do not recommend taking CoQ10 if you exercise. It has been shown to be very neurotoxic when there is a depletion of oxygen in the brain, which happens when you get out of breath from working out. Will you notice anything overnight? No, but long term... you're risking it.

[ConsiderThis]

Quite a long time ago I had extremely bad allergies... my face would swell up and I looked as if I was congenitally malformed... I would be miserable for a month or more in the spring and fall.

During one of those times a lady at the healthfood store told me about CoQ10 and I bought it and tried it.

It worked. I was surprised.

I don't think it was a perfect cure, but it helped a huge amount.

Then a few years later I found that a MegaB taken a few times a day COMPLETELY got rid of my allergies I forgot about CoQ10.

Last year someone on this forum suggested it to me... I forget in what context, so I ordered the 30mg ones, which aren't that expensive, and I take two or three at a time a couple to a few times a day.

I am doing much better, so perhaps they are contributing to that improvement.

I tend to think it's the Whey amino acids that are helping my nerves heal... and the serrapeptase reducing swelling in my back so that there's a lot LOT less back pain... but, I continue to buy and take the CoQ10 because whoever told me about it explained it in such a way that I can see how it could well be contributing to my improvement.

[Vowel Lady]

My neuro recommends 300 mgs. of this to help with migraine prevention. My husband's cardiologist recommends 150 mgs. to help with his needs. Overall, I think probably all adults should take the minimum dosage. From what I understand, if you are taking Statin medication (for high cholesterol), it's very important to take CoQ10.

[rose]

Hi, Ozone.

Where did you learn that?

rose

[ConsiderThis]

Hi InHisHands --

It's 3:31 a.m. and I'm awake because I bought the wrong strength of melatonin for me... darn it, I just realized this thread isn't about melatonin...

Well, let me just say that if you are thinking of trying melatonin, the smaller dose is more effective for sleep.

1mg works great for me.

but I accidentally bought the 3mg ones, and it's not working. If I remember correctly the higher dose can act as a stimulent... not what I was hoping for when I took it several hours ago...

[bruegger84]

yah the higher dose messes with ur sleep more than helps. i should know, and if your under 35 id be wary of the melatonin.

but to get back to q10, i would take that as i heard its good for the heart, but ill hafta see about that when mrsd gets back. she seems to be the most informed person on this site, in which i would trust her answers. for me its either mrsd or rose if i want to be informed of something. the exercise thing that ozone said seems to scare me, so for now ill just stick with my b12.

[mrsD]

I only have a few minutes left here... but I can throw my opinion out quickly...

Our bodies make CoQ-10 daily. I have never heard of this effect of harming
the brain during exercise. In fact CoQ-10 is a free radical quencher that is
helpful "during" exercise.

I will search this out further when I get back, but like rose I'd like some
documentation as to ozone's warning.