major studies of CoQ-10 for RSD.
However, for nerve neuropathy, there are studies for L-carnitine and acetyl carnitine.
CoQ-10 is used in high dose for Parkinson's, and some forms of ataxia.
CoQ-10 and carnitine are being used together today in products to prevent
damage and aging to mitochondria in cells. This is a antioxidant approach.
Since CoQ-10 is benign and has little if any negative effects, it certainly can not harm to try. But you would need high doses to get anywhere. I'd use it
with carnitine. Some products are already combined this way.
Both however are expensive, so it is a financial commitment. The PD board has people using high dose CoQ-10... you can ask there where they buy theirs.
I have seen products that claim for best results CoQ-10 and carnitine need some biotin as a helper. The product Juvenon has it added, for example. Biotin is a B vitamin.
There are hints that RSD is a calcium error in the nervous system, and
for a while now bisphosphonates are being tried for it:
and this is what pamidronate is:
The theory is that calcium is over active in the NMDA channels, which are pain
generators. Magnesium counters calcium at the NMDA channel to some extent, and making sure you have enough magnesium may be helpful , but not curative, since RSD is still not fully understood.
We have a magnesium thread here:
If you choose CoQ-10... choose one that is a soft gel cap with a label
that says it is enhanced absorption.
Powder forms are useless basically. The new Q-sorb and other names are
better. Here is one with a good formulation:
This supplier also has Carnitine
This is the same manufacturer as the Rx Carnitor.
I have used this supplier in the past. They are very good.