Krysse, one thing about Mestinon - for just about everyone who takes it, it is vitally important to find out what DOSAGE a patient's body can tolerate first (if the dosage is too high, you feel like you've been run over by a train - it's pretty obvious).
Once the dosage is established, then the TIME INTERVAL can be determined.
While a patient never wants to take a higher dosage than their body can handle, many days they may find that they need to take the Mestinon earlier than normal.
Some neurologists understand this and others don't.
As far as the prednisone goes, I think it's normal to start off in the hospital with a higher dose, then level off after the patient goes home.
When I was in the hospital, they had me on 60 mg/day, and not only was I ready to cut a b****, but I was eating anything that wasn't nailed down!
Now I'm down to 10 mg/day, and things are much better.
You do need to lower Prednisone dosages under a doctor's supervision.