If you are weight lifting to muscle fatigue as in body building regimens, you may be causing too much muscle cell breakdown. You also may be just getting to much adrenaline flowing through your body which can over-stress your brain. Either one could cause the foggy feelings.
You will likely do better with lighter weights with more reps than heavier weights to fatigue.
Regarding neuroplasticity, I would like to see some research about where neuroplasticity abounds and where it is less likely. From what I have read, most neuroplasticity claims refer to a brains ability to develop skills later in life that would have more normally developed during youthful maturing.
There is a big difference between repairing damaged brain circuits and developing or strengthening under-developed brain skills. Most research appears to focus on the later concept of neuroplasticity.
To a person with PCS, there is a good value to neuroplasticity. Those under-developed brain circuits can be strengthened to help overcome the other weaknesses that resulted from the brain injury. A comparison would be, If you have injured and permanently lost function and strength in your right arm and hand, you can strengthen and improve function in your left arm and hand to compensate.
Mark in Idaho
58 years old, retired due to disability, married 33 years, father of three, grandfather of four, Suffered a serious concussion at 10 years old (1965) stopped most driving after last concussion at 46 years old (2001), Post Concussion Syndrome/Multiple Concussion/Impact Syndrome with PTSD, immediate and short term visual and auditory memory problems, slowed processing speed, visual and auditory processing difficulties, insomnia, absence seizures, OCD, 14 concussions since first concussion at 8 years old, Taking paroxetine for 14 years and gabapentin for 12 years. Added L-Tryptophan and successfully stopped all paroxetine after 3 months of tapering down. I currently take 500 mgs of L-Tryptophan when I wake up, 500 mgs after breakfast with my vitamin regimen and 500 mgs late in the evening.
As of Nov 15th, Due to high stress issues resulting in PTSD, my docs put me on three meds. Clonazepam (Klonopin, a dreaded benzo but only for 30 days ) .125 mgs twice daily (Doc prescribed .25 mgs twice daily but half a tablet is doing good) , citalopram (Celexa), an SSRI , and olanzapine (Zyprexa), an atypical anti-psychotic before bed. I have lost over 30 pounds since mid July. The olanzapine is supposed to help me gain some of it back but it has just stopped the weight loss. They took me off the gabapentin. I am feeling better than I have in years.
I am also taking L-Theanine to help with GABA regulation
"Be Still and Know That I am God" Psalm 46:10