7.5 is the amount of hydrocodone. 750 is the amount of acetaminophen.
Are you sure the second number is 750 and not 650? (See below*)
Both are metabolized in the liver. While the hydrocodone itself
should not pose any problems to your liver, the acetaminophen can, and I'm surprised your doctor prescribed that high an amount of acetaminophen since there are so many dosage combinations available.
(Fall, 2011) safety limits for acetaminophen are no more than 1000 mg. within any six hour period
and no more than 3000 mg. within any 24 hour period
. (It is recommended that patients taking acetaminophen for more than 4 weeks take no more than 2600 mg. within any 24 hour period.)
Originally Posted by pebblebeach2
The maximum per day is as per the scripts 1 1/2 tablets
1½ times 750 = 1125, which already exceeds the maximum safe dose.
*(1½ times 650 = 975, which would fall within the safety limit)
If you can get by on less than the prescribed dose, then you might discuss with your doctor keeping the hydrocodone the same, but lowering the acetaminophen to 650, 500, or 325.
Patients who take acetaminophen longterm should get liver panels done periodically, 1-2 times/year.
If it is a concern, you can take an OTC anti-oxidant supplement called N-acetyl cisteine (NAC)
which may help protect your liver from damage from acetaminophen.