Go Back   NeuroTalk Support Groups > Health Conditions A - L > ALS > ALS News & Research

ALS News & Research For postings of news or research links and articles related to ALS

Hope for diabetes and Lou Gehrig's

Thread Tools Display Modes
Unread 11-07-2007, 04:33 PM   #1
In Remembrance
BobbyB's Avatar
Join Date: Aug 2006
Location: North Carolina
Posts: 4,609
Book Hope for diabetes and Lou Gehrig's

Hope for diabetes and Lou Gehrig's
11/07/2007 10:04 AM
By: Ivanhoe Newswire

SAN DIEGO -- In patients with type 1 diabetes, the pancreas stops making insulin, and patients must rely on injecting it to stay alive. Another illness, ALS, or Lou Gehrig's Disease, is even worse. It attacks the body's nerves and muscles, until patients eventually die. But now, there are two new breakthroughs for these diseases.

Ali Kutz's head is in the game, but there's something else she's always thinking about -- having type I diabetes.

"It's probably just the day in, day out; you never get a break from it," Kutz said.

"It's a complicated disease, and therefore, a cure would really be the best thing we could achieve," said Mattias von Herrath, M.D., a researcher at the La Jolla Institute for Allergy and Immunology in San Diego, Calif.

Hope for diabetes and Lou Gehrig's
In patients with type 1 diabetes, the pancreas stops making insulin, and patients must rely on injecting it to stay alive. Another illness, ALS, or Lou Gehrig's Disease, is even worse.

Now, researchers are testing a combo of two therapies in the lab. It's a one-two punch that could be used in people newly-diagnosed with diabetes. The first part -- an injection -- stops the immune system from attacking healthy beta cells that make insulin. The second part -- a vaccine -- enhances the body's response and allows the cells to regenerate. The diabetes therapy could be used in people recently diagnosed and those who have pre-diabetes.

"If you've heard, your skin will regenerate and so forth; I think the beta cells and the pancreas can do this, too," Dr. von Herrath continued.

Another breakthrough on the horizon -- one for ALS. People who get the devastating diagnosis are often told they only have a few years to live. Now, gene therapy could add years to their life.

"We hope to slow disease progression and, in our wildest dreams, we hope to dramatically to slow disease progression," added Don Cleveland, Ph.D., a neuroscientist at the University of California, San Diego.

Researchers have tested a molecular therapy in rats that turns off the bad gene in ALS. The drug is infused right into the spinal cord. It could be the first really effective treatment for the disease, and the first gene-silencing therapy used in people for a neurological disorder. The therapy could also be applied to diseases like Parkinson's and Alzheimer's.

"That will be quite different -- if we are successful -- quite different from therapies available," Dr. Cleveland said.

These two different solutions are helping researchers get one step closer to a cure. The diabetes and ALS trials in people will start around 2008. They've already proven effective in animals with virtually no side effects.

For more information:

Bonnie Ward
La Jolla Institute
(619) 303-3160

ALS, or Lou Gehrig's Disease:


ALS/MND Registry

BobbyB is offline  

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Dr. Cass Ingram's Natural Cures For Diabetes: Reverse diabetes quickly clouds z Diabetes / Insulin Resistance / Metabolic Syndrome 0 04-28-2007 06:17 PM
Study gives hope to Lou Gehrig's patients BobbyB ALS 0 12-01-2006 07:20 PM
Insulin Stem Cells Hold Hope for Diabetes Treatment DocJohn Health News Headlines 0 11-07-2006 08:20 PM

All times are GMT -5. The time now is 06:10 PM.
Brought to you by the fine folks who publish mental health and psychology information at Psych Central Mental Health Forums

The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider. Always consult your doctor before trying anything you read here.

Powered by vBulletin • Copyright ©2000 - 2016, Jelsoft Enterprises Ltd.

All posts copyright their original authors Community Guidelines Terms of Use Privacy Policy
NeuroTalk Archives