If you reread my comments you will see that I was comparing neurotransmitter nutrients to the L-tryptophan/5-HPT/serotonin chain.
One wants the nutrient to be as early in the chain of metabolism as possible. Then the body has the control over the amount that crosses the blood brain barrier. 5-HTP is not a normally occurring substance and disrupts the ability of the body to modulate the change to serotonin. Other neuro-transmitter nutrients may also interrupt this delicate mechanism.
Regarding the BBB, vaccines and the complications that go along with them have been shown to weaken the blood brain barrier. The high density membrane of the BBB has been shown to be attacked by the immune system as it tries to respond to vaccines. It is thought that this may be a part of the cause of MS, Lupus, and other auto-immune system disorders along with Autism spectrum.
As a "research scientist," you should have known that Neuroscience and Pharmasan Labs are not independent, They both have the same address and phone number and personnel:
373 280th St.
Osceola, WI 54020
PHARMASAN LABS, Inc
373 280th Street
Osceola, WI 54020
This information was taken from the web sites of each 'independent' organization. As for "Gold standard," conflict of interest seriously confuses the opportunity to establish a Gold standard.
Is the fox guarding the hen house?
Mark in Idaho
60 years old, retired due to disability, married 34 years, father of three, grandfather of four, Suffered a serious concussion at 10 years old (1965) stopped most driving after concussion at 46 years old (2001), Post Concussion Syndrome/Multiple Concussion/Impact Syndrome with PTSD, immediate/short term visual and auditory memory problems, slowed processing speed, visual/auditory processing difficulties, insomnia, absence seizures, OCD, 14 concussions since first concussion at 8 years old, Taking paroxetine for 14 years and gabapentin for 12 years. Added L-Tryptophan and stopped paroxetine after 3 months of tapering. I currently take 100 mgs of 5-HTP AM, 500 mgs of L-Tryptophan at noon.
As of Nov 15th, Due to high stress issues resulting in PTSD, docs put me on 3 meds. Clonazepam but only for 30 days ) .125 mgs twice daily (Doc presc. .25 mgs 2x daily but half a tablet is good) , citalopram (Celexa), an SSRI , and olanzapine (Zyprexa), an atypical anti-psychotic that usually causes weight gain before bed. I lost over 30 pounds since mid July. It just stopped the weight loss. Took me off the gabapentin.
May 2014, I am off the olanzapine due to a 6 fold price increase. Back on 600 mgs of gabapentin before bed.
Oct 2014, off the Celexa. The 5-HTP is doing much better and leaves me feeling normal as compared to being on an SSRI.
I am also taking L-Theanine to help with GABA regulation
"Be Still and Know That I am God" Psalm 46:10