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neurotransmitter assessment and adrenal gland test

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Unread 08-03-2009, 05:05 PM   #1
mhr4
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Hey All,

Just wanted to share with you that I just got my first neurotransmitter and adrenal assessment tests back from neuroscience. They both came back with interesting results. I did the 24 hour saliva cortical adrenal test and it showed that my adrenal glands are out of whack. I also did the morning urine test for the neurotransmitter test. It showed that I'm deficient in epinephrine, norepinephrine, dopamine and slightly deficient in seratonin. The ND I'm seeing for this has suggested I take a natural supplement for my adrenal glands and the suggested amino acid therapy from neuroscience for my neurotransmitter deficiency. Both of the therapies are pretty inexpensive -relatively speaking- so I thought I would give them a try. Not sure if this will work or not since this is very new science (except for the adrenal gland therapy) but I'm willing to give it a try. The doc did say that my adrenal glands being out of whack does make sense since I've put my body under so much stress with the PCS. She also has suspicions that my thyroid could also be out of whack, but she wants to see what happens with this first. I'll report back on here in a month for those who are interested. It seems that a lot of docs are excited for this therapy (of course, as with all things in the medical/science community, it doesn't come without it's critics also).

Also, if anyone has any experience with this, I would love it if you would share with us your experiences. Actually, I believe I got the idea from someone who posts on here regularly...Viny? Maybe???
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Unread 08-04-2009, 06:08 AM   #2
rydellen
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Im so interested in seeing how your progress develops! PLEASE let us know what happens with you!
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Unread 08-04-2009, 03:15 PM   #3
Mark in Idaho
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mhr4,

Have you had a thorough hormone panel done? It can be a big contributor to the other imbalances. Hormones can take a while to get in proper balance.

I have not been convinced that you can 'feed' your body neurotransmitters. The body makes them from other compounds.

I have looked into L-tryptophan as a supplement. The body routinely uses it to make 5-HTP and so on to serotonin. The studies show that you need to provide the nutrient in a form that is as far removed from the neurotransmitter as possible so that the body does the converting. The body knows how to modulate the end compound. An example is those who suffer from serotonin syndrome by taking 5-HTP in excess thus bypassing the body's modulating mechanism.

Thyroid tests should be repeated to find an average. Thyroid levels can be effected by other hormones.

There are two problems we have to consider.

One, our food supply can and does introduce toxins and hormones that disrupt our body's attempt to regulate itself.

Two, A brain injury can and often does disrupt the function of the pituitary gland thus messing up all of the functions down stream from the pituitary. Often, this is most evident during times of stress.

As an aside, I am skeptical of a lab that sell products to resolve their laboratory findings. I would like to see labs that are independent of the supply chain.

My wife has a lab that does the analysis, a physician who interprets the results and a separate supplier that compounds the nutrient/hormone. Her physician does not use the labs standards of "normal" as her standards.

If a science is valid, it will be the same at different labs. Until there are other labs doing the analysis, the science is to be questioned. I first started looking into "boutique" labs back in 1982. Some have continued to thrive and others collapse under the scrutiny of their peers. Some have become 'outlaws' by removing all claims to "diagnose, cure, treat, any disease or illness."

I would like to see a competitor to Neuroscience. Competition sharpens the scientific knowledge.
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59 years old, retired due to disability, married 33 years, father of three, grandfather of four, Suffered a serious concussion at 10 years old (1965) stopped most driving after last concussion at 46 years old (2001), Post Concussion Syndrome/Multiple Concussion/Impact Syndrome with PTSD, immediate and short term visual and auditory memory problems, slowed processing speed, visual and auditory processing difficulties, insomnia, absence seizures, OCD, 14 concussions since first concussion at 8 years old, Taking paroxetine for 14 years and gabapentin for 12 years. Added L-Tryptophan and successfully stopped all paroxetine after 3 months of tapering down. I currently take 500 mgs of L-Tryptophan when I wake up, 500 mgs after breakfast with my vitamin regimen and 500 mgs late in the evening.


As of Nov 15th, Due to high stress issues resulting in PTSD, my docs put me on three meds. Clonazepam (Klonopin, a dreaded benzo but only for 30 days ) .125 mgs twice daily (Doc prescribed .25 mgs twice daily but half a tablet is doing good) , citalopram (Celexa), an SSRI , and olanzapine (Zyprexa), an atypical anti-psychotic before bed. I have lost over 30 pounds since mid July. The olanzapine is supposed to help me gain some of it back but it has just stopped the weight loss. They took me off the gabapentin. I am feeling better than I have in years.

I am also taking L-Theanine to help with GABA regulation


"Be Still and Know That I am God" Psalm 46:10
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Unread 08-09-2009, 12:41 PM   #4
mhr4
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Mark,

I am getting the full hormone panel done in a few weeks. My 24 hour adrenal-cortical saliva test came back abnormal, so my hormones are probably also out of whack and need to be tested.

FYI: You don't actually feed your body neurotransmitters as they can't cross the blood brain barrier. You only feed your body the amino acid pre-cursers to neurotransmitters and it synthesizes them for you.

Also, neuroscience is independent of the of the lab that performs the analysis on the specimen. There are also about 5-6 competitors to neuroscience as well. Most just consider them the "gold standard" for this type of testing.




Quote:
Originally Posted by Mark in Idaho View Post
mhr4,

Have you had a thorough hormone panel done? It can be a big contributor to the other imbalances. Hormones can take a while to get in proper balance.

I have not been convinced that you can 'feed' your body neurotransmitters. The body makes them from other compounds.

I have looked into L-tryptophan as a supplement. The body routinely uses it to make 5-HTP and so on to serotonin. The studies show that you need to provide the nutrient in a form that is as far removed from the neurotransmitter as possible so that the body does the converting. The body knows how to modulate the end compound. An example is those who suffer from serotonin syndrome by taking 5-HTP in excess thus bypassing the body's modulating mechanism.

Thyroid tests should be repeated to find an average. Thyroid levels can be effected by other hormones.

There are two problems we have to consider.

One, our food supply can and does introduce toxins and hormones that disrupt our body's attempt to regulate itself.

Two, A brain injury can and often does disrupt the function of the pituitary gland thus messing up all of the functions down stream from the pituitary. Often, this is most evident during times of stress.

As an aside, I am skeptical of a lab that sell products to resolve their laboratory findings. I would like to see labs that are independent of the supply chain.

My wife has a lab that does the analysis, a physician who interprets the results and a separate supplier that compounds the nutrient/hormone. Her physician does not use the labs standards of "normal" as her standards.

If a science is valid, it will be the same at different labs. Until there are other labs doing the analysis, the science is to be questioned. I first started looking into "boutique" labs back in 1982. Some have continued to thrive and others collapse under the scrutiny of their peers. Some have become 'outlaws' by removing all claims to "diagnose, cure, treat, any disease or illness."

I would like to see a competitor to Neuroscience. Competition sharpens the scientific knowledge.
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Unread 08-09-2009, 03:47 PM   #5
Shelley
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While I do not have a brain injury I do have thyroid and adrenal problems.

I just did an adrenal saliva test and some thyroid panels.

I have read alot on both subjects and would love to talk to you more about your results and I will show you my results when I get them back this week.

Shelley
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Unread 08-10-2009, 10:46 AM   #6
vini
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best wishes with the therapy, it stands to reason that chemical imbalance plays a part in brain injury, as it dose in many other brain disorders , also the function of the cerebral spinal fluid and the choroid plexus, which is just starting to be fully understood as a nutrient transmitter, please let us know how you get on , but try to remember as with all things neurological, its slow to heal, but they may well be on to something , they can treat here !!
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Unread 08-10-2009, 12:31 PM   #7
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Hi Shelley,

That sounds good. Actually, my doc thinks I have always had thyroid/adrenal problems that are unrelated (but now could be related) to my brain injury. Let me know when you get your results and I'll give you my email address back channel.

Mike



Quote:
Originally Posted by Shelley View Post
While I do not have a brain injury I do have thyroid and adrenal problems.

I just did an adrenal saliva test and some thyroid panels.

I have read alot on both subjects and would love to talk to you more about your results and I will show you my results when I get them back this week.

Shelley
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Unread 08-10-2009, 02:51 PM   #8
Shelley
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HI mike,

I have read some things that a brain injury can cause pituitary problems that result in thyroid and adrenal problems.

Besides the adrenal test what is your doc ordering thyroid wise?
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Unread 08-10-2009, 05:36 PM   #9
mhr4
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TSH, free T3 and free T4. Any others I should be aware of? Thanks.


Quote:
Originally Posted by Shelley View Post
HI mike,

I have read some things that a brain injury can cause pituitary problems that result in thyroid and adrenal problems.

Besides the adrenal test what is your doc ordering thyroid wise?
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Shelley (08-10-2009)
Unread 08-10-2009, 08:46 PM   #10
Mark in Idaho
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mhr4,

If you reread my comments you will see that I was comparing neurotransmitter nutrients to the L-tryptophan/5-HPT/serotonin chain.

One wants the nutrient to be as early in the chain of metabolism as possible. Then the body has the control over the amount that crosses the blood brain barrier. 5-HTP is not a normally occurring substance and disrupts the ability of the body to modulate the change to serotonin. Other neuro-transmitter nutrients may also interrupt this delicate mechanism.

Regarding the BBB, vaccines and the complications that go along with them have been shown to weaken the blood brain barrier. The high density membrane of the BBB has been shown to be attacked by the immune system as it tries to respond to vaccines. It is thought that this may be a part of the cause of MS, Lupus, and other auto-immune system disorders along with Autism spectrum.

mhr4,

As a "research scientist," you should have known that Neuroscience and Pharmasan Labs are not independent, They both have the same address and phone number and personnel:

NeuroScience, Inc.
373 280th St.
Osceola, WI 54020
888-342-7272

PHARMASAN LABS, Inc
373 280th Street
Osceola, WI 54020
888-342-7272

This information was taken from the web sites of each 'independent' organization. As for "Gold standard," conflict of interest seriously confuses the opportunity to establish a Gold standard.

Is the fox guarding the hen house?
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Mark in Idaho
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59 years old, retired due to disability, married 33 years, father of three, grandfather of four, Suffered a serious concussion at 10 years old (1965) stopped most driving after last concussion at 46 years old (2001), Post Concussion Syndrome/Multiple Concussion/Impact Syndrome with PTSD, immediate and short term visual and auditory memory problems, slowed processing speed, visual and auditory processing difficulties, insomnia, absence seizures, OCD, 14 concussions since first concussion at 8 years old, Taking paroxetine for 14 years and gabapentin for 12 years. Added L-Tryptophan and successfully stopped all paroxetine after 3 months of tapering down. I currently take 500 mgs of L-Tryptophan when I wake up, 500 mgs after breakfast with my vitamin regimen and 500 mgs late in the evening.


As of Nov 15th, Due to high stress issues resulting in PTSD, my docs put me on three meds. Clonazepam (Klonopin, a dreaded benzo but only for 30 days ) .125 mgs twice daily (Doc prescribed .25 mgs twice daily but half a tablet is doing good) , citalopram (Celexa), an SSRI , and olanzapine (Zyprexa), an atypical anti-psychotic before bed. I have lost over 30 pounds since mid July. The olanzapine is supposed to help me gain some of it back but it has just stopped the weight loss. They took me off the gabapentin. I am feeling better than I have in years.

I am also taking L-Theanine to help with GABA regulation


"Be Still and Know That I am God" Psalm 46:10
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vini (08-12-2009)
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