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Gabapentin to Lyrica

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Unread 11-04-2010, 01:10 PM   #1
duffer
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Default Gabapentin to Lyrica

I am in the process of titrateing from Gapentin to Lyrica. Can anyone tell me what milligrams (mg) of Gapentin equal virtually the same amount of Lyrica.
In otherwords if I was taking 4000mg per day of Gabapentin (10 x 400mg)
what would be an equiivalent amount of Lyrica?
The reason I am changing drugs is that after 10 years it is no longer effective. So far Lyrica seems to be working. Right now 400 Lyrica and 2400 Gabapentin. Would like to know what amount of Lyrica to add and what amount of Gabapentn to reduce. It may just be trial and error.
Thanks for the replies.
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Unread 11-04-2010, 09:46 PM   #2
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I think that the max dose for Lyrica is 600 mg. a day. I made the switch myself and am very happy about it. Lyrica works better for me with less side effects, but we are all different. Hope it works for you too.
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Unread 11-05-2010, 09:19 PM   #3
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Originally Posted by rose_thorn98 View Post
I think that the max dose for Lyrica is 600 mg. a day. I made the switch myself and am very happy about it. Lyrica works better for me with less side effects, but we are all different. Hope it works for you too.
I realize Gabapentin and Lyrica are similar, some people respond better to one than the other, but just wondering if anyone has any knowledge on one of these drugs being a better choice in relation to long term effects, rate of absorbtion, safety, etc........
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Unread 11-05-2010, 11:40 PM   #4
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I have been having this shooting pain for only a couple of years, but now it is on a scale of 7-8. I have been taking Gabapentin, but I cannot handle more then 900mg, I get too tired, I look and feel drugged at work to and may loose my job. I am hoping the side effects of Lyrica are better. But no Dr seems to know what is wrong, one says I have neuropathy, but EMG test shows I do not. I have burning pain which started in my left big toe, then numbness in my left foot and calve. The pain was just annoying at first for about two years, now I am getting chills, and the pain level is 7-8. I had colitis, and had my colon removed so I know pain pretty well. My neurologist says it is due to irritation of my 5th lumbar but it is not bad enough to operate. Said to take narcotics which I never want to touch again. He will not give me the time of day, saying he made his diagnosis, now go to you PM. I would rather have my leg removed then go through this pain and drugs. Cannot maintain my job being s doped up. Sorry just venting here.
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Unread 11-06-2010, 12:07 AM   #5
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I think Lyrica has a better absorption rate, thats why you can take so much less of it than the Gabapentin.
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Unread 11-06-2010, 12:33 AM   #6
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Quote:
Originally Posted by duffer View Post
I am in the process of titrateing from Gapentin to Lyrica. Can anyone tell me what milligrams (mg) of Gapentin equal virtually the same amount of Lyrica.
In otherwords if I was taking 4000mg per day of Gabapentin (10 x 400mg)
what would be an equiivalent amount of Lyrica?
The reason I am changing drugs is that after 10 years it is no longer effective. So far Lyrica seems to be working. Right now 400 Lyrica and 2400 Gabapentin. Would like to know what amount of Lyrica to add and what amount of Gabapentn to reduce. It may just be trial and error.
Thanks for the replies.
supposed to be 10% per week . that is down 10%old up 10% new every week. Lyrica is very potent. Most stay clear after trying it no doubt going in to hard to fast. The side effects will diminish though it may take a very long time.
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Unread 11-06-2010, 01:07 AM   #7
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supposed to be 10% per week . that is down 10%old up 10% new every week. Lyrica is very potent. Most stay clear after trying it no doubt going in to hard to fast. The side effects will diminish though it may take a very long time.
I guess I'll stay on my Gabapentin, the increased dose seems to have kicked in, just within the last few days, not perfect by any means, but about a 50% reduction of sensations. It is amazing how eliminating the symptoms can help your state of mind. Especially if I am busy, moving a lot, when I sit down or am still it is more noticeable. So glad it stops when I sleep.

However if I have to keep increasing Gab, I am going to ask for Lyrica. I take 1200 mg. now and am getting fatter by the minute!
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Unread 11-06-2010, 07:46 AM   #8
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I think that for the the titration, the equivalence is 300mg Lyrica = 1800 mg gabapentin
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Unread 11-07-2010, 04:40 PM   #9
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Thanks, the information has been very helpful in giving me a guideline of how much of each drug to use while I titrate from Gabapentin to Lyrica.
I hope to have a positive report soon.
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Unread 11-09-2010, 08:20 PM   #10
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After 3 weeks on Lyrica it already is not working as well. I feel so discouraged. I'm on a low dose, but why does it seem that it stops working so fast. I had same problem with Gabapenin. I increased my Lyrica 2 days ago, but still no relief. How long will it take to begin working again?
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